A bacterial immunity protein directly senses two disparate phage proteins

by | Oct 16, 2024 | Uncategorized | 0 comments

Nature, Published online: 16 October 2024; doi:10.1038/s41586-024-08039-y

The antiphage defence protein CapRelSJ46 in Escherichia coli can directly bind and sense two completely unrelated and structurally different proteins using the same sensory domain, with overlapping but distinct interfaces.

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