SPP1 is required for maintaining mesenchymal cell fate in pancreatic cancer

by | Sep 24, 2025 | Uncategorized | 0 comments

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Nature, Published online: 24 September 2025; doi:10.1038/s41586-025-09574-y

Mutual paracrine regulation of the cytokines GREM1 and SPP1 mediate mesenchymal and epithelial cell fate in pancreatic cancer.

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