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Modular in vivo antibody–ADC click to reverse drug resistance in tumours

by Suzi Wilson | Jul 15, 2026 | Uncategorized | 0 comments

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Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10789-w

In vivo ligation of clinically used therapeutic antibodies via bioorthogonal click chemistry to antibody–drug conjugates leads to enhanced antitumour activity in heterogeneous and treatment-resistant tumours.

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