Nature is the world’s foremost international weekly scientific journal and is the flagship journal for Nature Portfolio. It publishes the finest peer-reviewed research in all fields of science and technology based on its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance, and surprising conclusions. Nature publishes landmark papers, award-winning news, leading comments, and expert opinions on important, topical scientific news and events that enable readers to share the latest scientific discoveries and evolve the discussion amongst the global scientific community.
Lactate helps cancer cells resist chemotherapy
Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02731-9
The molecule lactate is a waste product of the metabolism of sugar without oxygen — a metabolic pathway preferentially used by cancer cells to generate their energy. Metabolomics analysis reveals that lactate in tumour cells promotes resistance to chemotherapy, and sheds light on the molecular mechanism that underlies this unexpected role of lactate in cancer.
How to harness AI’s potential in research — responsibly and ethically
Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02762-2
Artificial intelligence is propelling advances in all areas of science. But vigilance is needed, warn four researchers at the leading edge.
Science treasures from Microsoft mogul up for auction — and researchers are salivating
Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02769-9
Spacesuits, historic computers and more from the estate of the late Paul Allen are going on sale.
AI analysed 1,500 policies to cut emissions. These ones worked
Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02717-7
Only 63 climate change interventions led to significant reductions in carbon emissions.
Stone Age builders had engineering savvy, finds study of 6000-year-old monument
Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02776-w
A survey of the Dolmen of Menga suggests that the stone tomb’s Neolithic builders had an understanding of science.
Story time
Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02764-0
Family matters.
What Science and Nature are good for: causing paper cuts
Nature, Published online: 23 August 2024; doi:10.1038/d41586-024-02297-6
Experiments reveal that human skin is most reliably cut by specific thicknesses of paper, including the kind used to print certain high-profile journals.
The meaning of the Anthropocene: why it matters even without a formal geological definition
Nature, Published online: 26 August 2024; doi:10.1038/d41586-024-02712-y
Even though geologists have rejected the designation of an Anthropocene epoch, the idea of a major planetary transition in the mid-twentieth century remains useful across physical and social sciences, the humanities and policy.
Birth of protein folds and functions in the virome
Nature, Published online: 26 August 2024; doi:10.1038/s41586-024-07809-y
Structural comparison of predicted viral protein structures with known protein structures suggests taxonomic relationships and functions for up to 25% of unannotated viral proteins, including many with putative functions in host immune evasion.
How I create virtual twins for fabrics and furniture
Nature, Published online: 26 August 2024; doi:10.1038/d41586-024-02763-1
Jakub Cech creates digital versions of materials for use in the virtual world.